Panosteitis
literally means "inflammation of all bones". It
is a disease of the fatty bone marrow which causes secondary
changes to the long bones. Affected dogs exhibit
intermittent lameness in one or more legs, either simultaneously
or sequentially. Lameness in one leg may last for days to
weeks, then another leg may be affected. This cycle of
lameness typically lasts three months. There can be
multiple cycles, with months in between. The disease
generally disappears by the time the dog is two years old.
Canine
panosteitis occurs
spontaneously in young, large breed dogs, especially German
Shepherds. It has also been reported in the Bassett Hound,
Scottish Terrier, Great Dane, St. Bernard, Doberman Pinscher, German
Shorthaired Pointer,
Irish Setter, Airedale, Golden Retriever, Labrador Retriever,
Samoyed, and Miniature Schnauzer. The
disease has also been called juvenile osteomyelitis, enostosis,
and eosinophilic panosteitis.
Signs and Symptoms
The
main sign of canine panosteitis
is sudden lameness in one or more legs in a young dog, with no
history of trauma. The average age of onset is 5 - 12
months, although it has been reported in dogs as young as two
months and as old as five years. It is more common for males
to be affected than females, and in females, the panosteitis
often occurs with the first estrus.
The
lameness is caused by pain, which can range from slight to severe,
with lameness also being minimal to severe. Affected dogs
may also be depressed and lose their appetite.
Causes
The
exact cause of panosteitis
is unknown. Genetics seems to be a factor, especially in German
Shepherds where the disease is especially prevalent. Other
suggested causes include diet, stress, infection, and metabolic or
autoimmune problems. High calcium, high protein, and/or high
calorie diets have been suggested as a cause, but there does not
appear to be general agreement on this.
Risk Factors
Panosteitis
in related dogs (genetics) and diet may be risk factors.
Diagnostic Tests
Panosteitis
can be a difficult disease to diagnose. The lameness can
shift from limb to limb. X-rays can show changes in the
middle of the long bones, but the x-rays can be difficult to
interpret if taken at early or late stages of the disease.
There is typically pain when the shaft of the affected bones is
pressed firmly.
Treatment
Guidelines
Conventional
Treatments: Pain killers or non-steroidal
anti-inflammatory drugs are used to relieve the pain. If
these are not effective, corticosteroids are sometimes used.
Alternative/holistic:
Some suggest using fish or salmon oil, borage oil, and bromelian
as anti-inflammatory agents.
Management
Panosteitis
will eventually go away, with or without treatment.
Therefore the aim is to keep the dog comfortable.
The
Suggested Links (below) have additional advice on diet and other
management tips.
References
-
Timothy
M. Lenehan, David C. VanSickle, and Darryl N. Biery. Chapter
49, Canine Panosteitis,
in Textbook of Small Animal Orthopaedics. University of
Pennsylvania.
-
Panosteitis,
in The Merck Veterinary Manual.
-
Panosteitis,
in Provet Pet Health Information http://www.provet.co.uk/health/diseases/Panosteitis.htm
-
http://onibasu.com/archives/kn/125792.html
HELPFUL
LINKS ON PANOSTEITIS
International
Veterinary Information Service (IVIS) - http://www.ivis.org/special_books/ortho/chapter_49/IVIS.pdf
http://www.vetinfo.com/dencyclopedia/depano.html
http://www.vetinfo4dogs.com/dpano.html
http://www.labradorwell.com/FAQuestions.html#panosteitis
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